| Major League Soccer | San Diego | Vancouver Whitecaps | 24‑May | 2-4 | |
| Major League Soccer | San Diego | FC Cincinnati | 17‑May | 3-3 | |
| Major League Soccer | San Diego | Austin | 14‑May | 5-0 | |
| Major League Soccer | Seattle Sounders | San Diego | 10‑May | 1-1 | |
| Major League Soccer | San Diego | Los Angeles FC | 03‑May | 2-2 | |
| Major League Soccer | San Diego | Portland Timbers | 26‑Apr | 1-2 | |
| Major League Soccer | Houston Dynamo | San Diego | 23‑Apr | 1-0 | |
| Major League Soccer | Real Salt Lake | San Diego | 19‑Apr | 4-2 | |
| Major League Soccer | San Diego | Minnesota United FC | 12‑Apr | 1-2 | |
| Major League Soccer | San Jose Earthquakes | San Diego | 05‑Apr | 3-0 | |
| Major League Soccer | San Diego | Real Salt Lake | 22‑Mar | 2-2 | |
| CONCACAF Champions League | Toluca | San Diego | 19‑Mar | 4-0 | |
| Major League Soccer | FC Dallas | San Diego | 15‑Mar | 3-3 | |
| CONCACAF Champions League | San Diego | Toluca | 12‑Mar | 3-2 | |
| Major League Soccer | Sporting Kansas City | San Diego | 08‑Mar | 0-1 | |
| Major League Soccer | San Diego | St. Louis City | 02‑Mar | 2-0 | |
| Major League Soccer | San Diego | CF Montreal | 22‑Feb | 5-0 | |
| CONCACAF Champions League | U.N.A.M. - Pumas | San Diego | 11‑Feb | 1-0 | |
| CONCACAF Champions League | San Diego | U.N.A.M. - Pumas | 04‑Feb | 4-1 | |
| Friendlies Clubs | San Diego | San Jose Earthquakes | 24‑Jan | 2-0 | |
