| Premier League 2 Division One | Manchester United U21 | Chelsea U21 | 02‑Mar | 0-2 | |
| Premier League 2 Division One | Leicester City U21 | Manchester United U21 | 23‑Feb | 1-4 | |
| Premier League 2 Division One | Manchester United U21 | Derby County U21 | 06‑Feb | 1-1 | |
| Premier League 2 Division One | West Bromwich Albion U21 | Manchester United U21 | 02‑Feb | 1-5 | |
| Premier League 2 Division One | Manchester United U21 | Brighton U21 | 26‑Jan | 1-1 | |
| Premier League International Cup | Manchester United U21 | Sporting CP B | 20‑Jan | 3-2 | |
| Premier League 2 Division One | Fulham U21 | Manchester United U21 | 16‑Jan | 2-2 | |
| Premier League 2 Division One | Wolves U21 | Manchester United U21 | 12‑Jan | 1-4 | |
| Premier League International Cup | Manchester United U21 | Borussia Dortmund II | 19‑Dec | 2-0 | |
| National League Cup | Tamworth | Manchester United U21 | 16‑Dec | 3-0 | |
| Premier League International Cup | Manchester United U21 | Anderlecht U21 | 02‑Dec | 1-4 | |
| National League Cup | Solihull Moors | Manchester United U21 | 25‑Nov | 4-1 | |
| EFL Trophy | Notts County | Manchester United U21 | 04‑Nov | 0-2 | |
| Premier League 2 Division One | Manchester United U21 | Blackburn Rovers U21 | 31‑Oct | 0-4 | |
| National League Cup | Rochdale | Manchester United U21 | 28‑Oct | 0-2 | |
| Premier League 2 Division One | Manchester United U21 | Tottenham Hotspur U21 | 25‑Oct | 4-1 | |
| EFL Trophy | Barnsley | Manchester United U21 | 21‑Oct | 5-2 | |
| Premier League 2 Division One | Everton U21 | Manchester United U21 | 03‑Oct | 1-2 | |
| EFL Trophy | Lincoln | Manchester United U21 | 30‑Sep | 3-0 | |
| Premier League 2 Division One | Manchester United U21 | Crystal Palace U21 | 27‑Sep | 4-1 | |
| Premier League International Cup | Manchester United U21 | Athletic Club II | 24‑Sep | 2-1 | |
| Premier League 2 Division One | Liverpool U21 | Manchester United U21 | 21‑Sep | 1-2 | |
| National League Cup | Brackley Town | Manchester United U21 | 16‑Sep | 2-1 | |
| Premier League 2 Division One | Manchester United U21 | Manchester City U21 | 31‑Aug | 2-1 | |
| Premier League 2 Division One | Manchester United U21 | Norwich City U21 | 22‑Aug | 4-2 | |
| Premier League 2 Division One | Middlesbrough U21 | Manchester United U21 | 18‑Aug | 0-1 | |
| Friendlies Clubs | Rochdale | Manchester United U21 | 02‑Aug | 1-1 | |
