| Premier League 2 Division One | Manchester United U21 | Away | 25‑Oct 12:00 | |
| EFL Trophy | Cheltenham | Away | 28‑Oct 19:00 | |
| Premier League 2 Division One | Southampton U21 | Home | 01‑Nov 13:30 | |
| Premier League 2 Division One | Fulham U21 | Away | 08‑Nov 12:00 | |
| Premier League 2 Division One | West Ham United U21 | Home | 09‑Jan 19:00 | |
| Premier League 2 Division One | Burnley U21 | Away | 16‑Jan 19:00 | |
| Premier League 2 Division One | Stoke City U21 | Away | 23‑Jan 19:00 | |
| Premier League 2 Division One | Everton U21 | Home | 30‑Jan 19:00 | |
| Premier League 2 Division One | Birmingham City U21 | Home | 06‑Feb 19:00 | |
| Premier League 2 Division One | Blackburn Rovers U21 | Away | 16‑Feb 19:00 | |
| Premier League 2 Division One | Norwich City U21 | Home | 20‑Feb 19:00 | |
| Premier League 2 Division One | Liverpool U21 | Away | 01‑Mar 14:00 | |
| Premier League 2 Division One | Middlesbrough U21 | Home | 06‑Mar 19:00 | |
| Premier League 2 Division One | Leeds United U21 | Away | 16‑Mar 19:00 | |
| Premier League 2 Division One | Wolves U21 | Home | 10‑Apr 19:00 | |
