| Ghana | Mins | Sao Tome and Principe |
|---|---|---|
 N. Opoku | 12" | |
| J. Ayew (Pen) | 31" | |
| 55" |  Vavá Pequeno | |
| 59" | Traure | |
| A. Baba | 60" | |
| 83" | Iniesta | |
| Justice Blay | 85" |
| Ghana | Sao Tome and Principe | ||
|---|---|---|---|
| Starting XI | |||
| 4-2-3-1 | 4-3-3 | ||
| G | 16. Razak Abalora | G | 1. Aldair D'Almeida |
| D | 2. Benson Anang | D | 3. Vavá Pequeno |
| D | 4. Nicholas Opoku | D | 2. Ivonaldo Viegas |
| D | 27. Ismail Ganiyu | M | 8. Joazhifel Soares |
| D | 17. Abdul Baba Rahman | D | 5. Jardel Nazare |
| M | 11. Mubarak Wakaso | M | 7. Joel Neves |
| M | 5. Thomas Partey | M | 15. Ricardo Cardoso |
| F | 10. André Ayew | M | 21. Nilton Pequeno |
| F | 20. Mohammed Kudus | F | 10. Luís Leal |
| F | 7. Osman Bukari | F | 11. Zé Carlos Semedo |
| F | 9. Jordan Ayew | F | 9. Edmilson Viegas |
| Subs | |||
| G | 1. Ibrahim Danlad | G | 99. Gilmar Tavinho |
| G | 12. Richard Ofori | G | 12. Nilson Taty |
| D | 19. Joseph Adjei | D | 13. Dilson |
| M | 24. Justice Blay | M | 17. Iniesta |
| M | 18. Gladson Awako | M | 22. Adjeil Neves |
| M | 29. Kwame Poku | M | 18. Eduardo Varela |
| F | 26. Kwame Opoku | 20. Zé Varela | |
| F | 14. Emmanuel Boateng | 19. Tinho | |
| F | 25. Emmanuel Gyasi | 4. Traure | |
| F | 30. Kwasi Okyere Wriedt | 6. Gualdino Mauro | |
| F | 15. Joseph Esso | 6. | |
World Africa Cup of Nations - Qualification 2021